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It was important to note that reduction in body weight did not appear to reach a plateau at the end of the treatment and all significant reduction in weight from baseline was seen in all groups administered cagrilintide, in comparison to the placebo group

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It must not be taken alongside monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOI treatment, due to the risk of hypertensive crisis

Ideally, youd want labs done at the beginning and again with each dose increase, or at least every 36 months, to make sure the medication is working safely and not causing unwanted side effects

10.1016/S0002-9440(10)64051-5 Am J Pathol