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Most side effects show up early or after a dose increase, and most are gastrointestinal

It's a once-weekly injection, and choosing a consistent day helps establish a routine

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Figure 1 ALC reduced plasma TC and LDL-C levels in C57BL/6J mice fed a high-cholesterol diet Building upon the clinical observations, among the differential plasma metabolites of patients with hyperlipidemia, ALC was significantly downregulated and negatively correlated with plasma LDL-C

However, for high-throughput laboratories, the time savings from eliminated reconstitution steps and the ability to use reagent across multiple days may offset the per-assay cost difference