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Centroblasts go through cycles of somatic hypermutation and rapid proliferation, later their division rate slows down and their expression of CXCR4 is down-regulated, but immunoglobulins of them gradually began to be highly expressed, and then they migrate to LZ where the B cell density is relatively low
Kulkarni SS, Watson EE et al (2019) Diselenideselenoester ligation for chemical protein synthesis
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