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For all of the participants, squatting was associated with the shortest time spent moving stool and the easiest sensation of bowel emptying (Sikirov 2003)

Increased TMAO levels are caused by lower clearance and increased synthesis as a result of gut dysbiosis, a weakened intestinal barrier, and increased hepatic enzyme activity

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The quality of the preparation is based on the pharmaceutical standard: purity 98% HPLC, identity confirmed by mass spectrometry, COA available for each batch