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Nature 349:117127 Dyson MR, Shadbolt SP, Vincent KJ, Perera RL, McCafferty J (2004) Production of soluble mammalian proteins in Escherichia coli: identification of protein features that correlate with successful expression
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A 2020 review cites studies that indicate extravasation occurs in Injection site reactions may get better within a few days
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As explained by Alibert: During the first stage the pebbles brought the mass
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