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Sudakov views DSIP as one of the 4 main substances, responsible for the stress-resistance of the organism, another 3 being substance P, prolactin and beta-endorphin

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In the 536 bp site of the proximal promoter of GGT, a binding site exists between p50, TNF- and Sp1, regulated by the activation of the NF-B signaling pathway, thereby promoting expression of GGT and inducing inflammatory response (Fig