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In the most severe cases patients have elevated serum levels of C10:2-carnitine

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Gabapentin attenuates intestinal inflammation: role of PPAR-gamma receptor

However, other studies (e.g., JCAD Online 2019) reported variable results and advised caution with unregulated supplements

Connexin 32 and connexin 47 knockout (KO) mice exhibited exacerbated EAE pathology, with connexin 47 KO animals showing an earlier onset and increased disease severity