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Magnesium acts as a natural NF-B inhibitor, helping to decrease the production of inflammatory substances in the brain

Tirzepatide, the active ingredient in Zepbound, was found to have similar effects during the SURMOUNT-1 trial

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4.2 Fatty acid -oxidation suppression in kidney repair The increase in glycolysis levels in repaired kidneys is always associated with the dysregulation of lipid metabolism (Harzandi et al., 2021)

Insulin resistance index (HOMA-IR) was calculated by the formula of fasting insulin (FIns, U/ml) fasting blood glucose (FBG, mmol/L)/22.5 as described in the previously published study (27)