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Due to their bis-allylic methylene groups, PUFAs are highly susceptible to ROS attack compared to saturated fatty acids (SFAs) and monounsaturated fatty acids (MUFAs), leading to oxidation, hydroxyl group formation, and ultimately a peroxidized state (Su et al., 2019

Semin Cell Dev Biol 108:1423

Phospholipids derived from soy or sunflower are a common and well-tolerated source for true liposomal formulations

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