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Here is what the current research can actually support

Growth hormone secretion follows a circadian pattern, with the largest pulses occurring shortly after the onset of deep sleep. Van Cauter et al., Journal of Clinical Investigation Best Times to Administer Sermorelin Before Bed (Most Common) Administering Sermorelin 30 minutes before sleep helps amplify the bodys largest natural GH pulse , leading to better recovery and fat metabolism during the night

doi: 10.1002/mco2.416 48 GanJChenJMaR-LDengYDingX-SZhuS-Yet al

Protein-forward meals, water, and GLP-1 supplement support, plus lower-fat foods during escalation, all help with tolerance

Jackson and Theiss, 2020