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NAC supplementation (600 mg/day) has been shown to improve flow-mediated dilation in patients with chronic heart failure in a small RCT (Andrews et al., J Am Coll Cardiol, 2001) [65]
Many patients report reduced appetite and increased feelings of fullness within the first week of treatment, though individual experiences vary considerably
Therapeutic doses of acetaminophen with co-administration of cysteine and mannitol during early development result in long term behavioral changes in laboratory rats
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