The results from the group are as followed: STEP 1: The mean change in body weight for those taking the semaglutide from the baseline was 14.9% over 68 weeks compared to a 2.4% decrease for those taking the placebo
In summary, rational design has led to the development of two long-acting GLP-1 analogs, liraglutide and semaglutide, that have made a vast contribution to the management of T2D in terms of improvements in glycemic control, body weight, blood pressure, lipids, beta-cell function, and CV outcomes
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