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Past, present and future
Di norma, in caso di piena funzionalit metabolica, una persona di 70 chilogrammi (kg) produce 11-34 milligrammi (mg) di carnitina al giorno (die), raggiungendo un contenuto corporeo totale di circa 20 g quasi interamente localizzato nelle cellule muscolari scheletriche
Arora S , Senapati J, Loghavi S, Reville PK, Wang B, Kadia TM, DiNardo CD, Pemmaraju N, Yilmaz M, Jabbour JE, Short NJ, Montalban-Bravo G, Maiti A, Tang G, Sasaki K, Borthakur G, Alvarez J, Pierce S, Nogueras Gonzlez GM, Ning J, Issa GC, Andreeff M , Ravandi F, Garcia-Manero G, Abbas HA, Daver N
Erastin, a ferroptosis inducer, binds to VDAC2 and VDAC3 on the outer mitochondrial membrane, inducing mitochondrial dysfunction and oxidant release, ultimately triggering ferroptosis in tumor cells
Senescent cells are removed with the help of this process (2)
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