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The GLP-1 revolution: Novo Nordisk & Lilly now lead with semaglutide (Wegovy) & tirzepatide (Zepbound), showing double-digit weight loss percentages with fewer risks
To overcome these limitations, the researchers designed and synthesized novel small molecules with improved metabolic stability, BBB penetrability, and oral activity
A phase 3 study conducted on patients with T2DM has shown that tirzepatide improves HbA1c levels at all doses (515 mg)
Cyanocobalamin is the most stable and least expensive form of B12, widely used in oral supplements and injections
The compounds remove a metabolic bottleneck
