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This usually subsides as the body adjusts, and adequate hydration paradoxically helps reduce retention

The symptoms and clinical effects of these diseases vary depending on the type and individual differences

doi: 10.1016/j.neuroscience.2011.02.023 84 FortinSMChenJCPetticordMCRagozzinoFJPetersJHHayesMR

There are also alternative proline catabolic pathways that cleave proline into two-carbon molecules, yet are NAD + dependent, so these metabolic pathways are suppressed in the gdh3 / gdh3 mutant