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Exp Ther Med 2016;11(3):1123-1127

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However, among other effects, it is in part able to suppress nausea, by acting directly on the Area Postrema, (the same part of the brain that we introduced which regulates vomiting in humans) [24] , which is thought to be a contributing factor as to why dual GLP1R/GIPR agonists are able to act synergistically

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Gastrointestinal adverse events of tirzepatide in the treatment of type 2 diabetes mellitus: a meta-analysis and trials sequential analysis