does semaglutide cause birth defects Millions of women of reproductive age are now taking GLP-1 medications like and liraglutide for diabetes and weight management. A new systematic review in JACC: Advances asks an increasingly important question — Ozempic and Fertility: Effects on

This causes increased pressure in the veins which can lead to fluid buildup in the legs

Higher-likelihood alternative causes: In UK clinical guidance, GSM is a common and under-treated driver of dryness, dyspareunia and tissue fragility, and should be actively assessed, particularly in peri-/post-menopausal patients or those with iatrogenic hypo-oestrogenism

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Importantly, the Summary of Product Characteristics for both Wegovy and Saxenda warn that acute kidney injury has been reported in association with dehydration from these gastrointestinal adverse events

Diabetologia 55(9):23432347