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Nanoparticles such as liposomes have been used for drug delivery, as they can minimize chemical degradation, improve drug permeability, and achieve the necessary blood drug concentration at the site of action [151,152,153]
MTs in obesity MTs in obesity and public health impact According to the World Health Organization, obesity has become a significant public health threat of the 21 st century and its prevalence has tripled in developed countries since the 1980s, making it one of the greatest health challenges we face today, and the number of those affected continues to rise at an alarming rate
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Macrophage subsets (MAC.1, MAC.2) were distinguished by high expression of CD68, CEBPB , and FCER1G , while a third cluster (Inf.MAC) expressed NLRP3 and showed an inflammatory, cytokine-enriched, and pro-angiogenic profile with markers like IL1B and CCL3
