The approval was based on data from the SUNSHINE and SUNRISE studies, which together showed that Cosentyx-treated patients achieved significantly higher rates of clinical response compared to placebo
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Drugs such as Wegovy mimic the actions of glucagon-like peptide-1 (GLP-1), a hormone secreted by the gastrointestinal tract, and are referred to as GLP-1 agonists facilitate weight loss by stimulating insulin secretion, delaying the emptying of the stomach contents, and reducing hunger
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4.1 Mechanisms of flavonoid-miRNA interaction Flavonoids can modulate miRNA expression via several mechanisms, either directly by interacting with signaling molecules or indirectly through epigenetic regulation