In the STEP clinical trial program for semaglutide, involving over 4,500 participants, serious kidney-related adverse events were uncommon and typically associated with severe dehydration from gastrointestinal symptoms
Rare but serious reactions include chest pain, irregular heartbeat, or paradoxical bronchospasm (worsening wheeze), all of which require immediate medical attention
Studies demonstrate protection against brain edema, reduced inflammatory cytokines TNF- and IL-1, and enhanced neuronal survival following injury
Enzimas pancreticas: En los estudios fase 3 controlados con placebo de DMT2, el tratamiento con tirzepatida dio lugar a un aumento medio de la amilasa pancretica del 33% al 38% respecto al valor inicial y de la lipasa del 31% al 42%
Yin X, Qiu Y, Zhao C, Zhou Z, Bao J, Qian W