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NaCl helps the osmotic component, but a buffered version of NAD+ addresses the actual cause. Tesamorelin is the one people get backwards: its FDA label specifies sterile water, but that is regulatory convenience, not the better diluent

Liu RY, Zhou JN, Hoogendijk WJG et al (2000) Decreased vasopressin gene expression in the biological clock of Alzheimer disease patients with and without depression