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But the $500-a-month bill made the drug unaffordable

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Special attention should be paid to standardizing extracts, determining optimal dosing, and investigating potential herb-drug interactions

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Proper laboratory handling procedures are recommended to maintain sterility and overall product quality after opening

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However, TB500 is not without risk

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2-oxoglutarate, a product of the catabolic reaction of the NADP-GDH and an intermediate of the TCA cycle, inhibits the binding of GdhR to gdhA P2 (Pagliarulo et al., 2004)

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