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In fact, the vascular endothelium grows in the body as a monolayer of cells lining the inner surface of blood vessels within a 3D microenvironment supported by collagen and proteoglycan ECM [241, 242]
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457 The basket trial of KY100001K uses IDH mutation as the core enrollment criterion, overcoming tumor tissue-of-origin constraints to efficiently evaluate its efficacy and safety across multiple cancer types, thereby accelerating the precise development of rare molecular subtypes and providing a rationale for pancancer applications
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