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NNMT has been explored as a target in obesity, insulin resistance, and age-related metabolic decline, supporting the rationale for translational research into body composition and performance contexts (Kannt & Pfenninger, Frontiers in Physiology )

Originally developed by Russian scientist Professor Vladimir Khavinson in the 1980s, Epithalon is based on the naturally occurring peptide epithalamin found in the pineal gland

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Therefore, the intracellular levels of H 2 O 2 under 1% O 2 conditions were further evaluated through CLSM and assay kits