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During the item generation and discussion and clarification phases, the experts identified 14 distinct challenges: costs, supply challenges, lack of evidence, polypharmacy, barriers to prescription, lack of knowledge, adherence concerns, aversion to injection therapy, clinical inertia, titration needs, perceived health state, fear of adverse effects, lack of clinical guideline recommendations, and lack of measurable outcomes to guide therapy
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Reich, E., Franklin, R
In the cardiovascular system, GLP-1R engagement exerts cardioprotective effects and attenuates systemic inflammation
The metastasis may cause impairment of the function of a corresponding organ, such as dyspnea, cough, chest pain, bone pain, etc
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