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Similar content being viewed by others 1 Introduction Vitamin B12 is essential for DNA synthesis, methylation, and folate metabolism, especially to convert folate to its active form, synthesize purines, convert homocysteine into methionine, and produce S-adenosylmethionine, which is involved in over 100 methylation reactions
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We upregulated the expression of GCLC, GSS, or SLC7A11 in VRK2-KD PC cells, and investigated the effects of these genes on cell viability, ROS and GSH levels when provided exogenous ROS ter-tbutyl hydroperoxide (TBHP)
