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Based on these results, scientists at Tokushima University Hospital and Suzuka University of Medical Science, in Japan, conducted a long-term Phase 2/3 clinical trial (NCT00444613) to evaluate the efficacy and safety of ultra-high-dose methylcobalamin treatment for ALS

6.1.1 -synuclein-directed therapeutics Several therapeutic strategies are currently focused on directly inhibiting the aggregation of -syn

However, it is important to be aware of potential side effects, even if they are rare

Intensive protocols require closer medical monitoring to ensure appropriate tolerance and to assess therapeutic response

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