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Analyses were stratified by obesity class (BMI = 30-39.9 and BMI 40)
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However, attempts were also made to stabilise the GLP-1 molecule against DPP-4 and also to prevent its high renal clearance rate, which in itself would result in an IV half-life of 30 min
Researchers continue investigating how GLP-1 signaling contributes to metabolic regulation and nutrient processing
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