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After analyzing complete trial data from the New England Journal of Medicine and clinical experience managing 340+ patients on GLP-1 and GIP agonists, one pattern emerged: patients who understand the timeline and prepare for peak side effects succeed

Williams et al Circulation and degradation of GIP and GLP-1 Hormone Metab Res

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For example, the North American Thrombosis Forum found that patients with inflammatory bowel disease (IBD) may have a 3-4 times higher risk of developing thrombosis (blood clots) than people without IBD. It is well-documented that Ozempic can cause significant gastrointestinal side effects, from diarrhea to gastroparesis