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It is essential to recognise that the presence of blood in stool whilst taking Ozempic warrants thorough clinical evaluation, as multiple potential causes existsome potentially related to the medication's gastrointestinal effects and others entirely independent of semaglutide therapy
Evidence-Based Complementary and Alternative Medicine, 2016 , 4305074
Notably, Eli Lillys 2023 release of tirzepatide marked the first FDA-approved dual GIP and GLP-1 receptor agonist
The clinical trial programme for semaglutide 2.4 mg (STEP trials), which included over 4,500 participants followed for up to 68 weeks as documented in the European Public Assessment Report (EPAR), did not identify diverticulitis as a treatment-emergent adverse event occurring at rates higher than placebo
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