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Common symptoms of a lower urinary tract infection (cystitis) include: A persistent, strong urge to urinate A burning sensation or pain when passing urine (dysuria) Passing frequent, small amounts of urine Cloudy, dark, or strong-smelling urine Blood in the urine (haematuria), which may appear pink or red Pelvic discomfort or pressure, particularly in women A feeling of incomplete bladder emptying Upper urinary tract infections (pyelonephritis) , affecting the kidneys, are more serious and may present with additional symptoms such as high fever, chills, nausea, vomiting, and pain in the back, side, or groin

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Las autoridades sanitarias, como la Administracin de Alimentos y Frmacos (FDA) en Estados Unidos o el Instituto Nacional para la Excelencia en Salud y Atencin (NICE) en Reino Unido, sealan que el frmaco es seguro y efectivo para el control de peso crnico en adultos con obesidad que presentan al menos un trastorno vinculado con ese sobrepeso, como hipertensin o diabetes tipo 2

Diminished parasympathetic modulation of the heart resulting in increased HR was also observed in response to intracerebroventricular infusion of exendin-4 in mice [36]