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10.1371/journal.pone.0154483 121 ZhouZ

SAC, a major organosulfur compound in aged garlic extract, prevented renal damage caused by ROS in cisplatin-treated rats, by limiting cisplatin-induced reduction of glutathione level, Nrf2 expression, and activity of several antioxidant enzymes (catalase, glutathione reductase, glutathione peroxidase) (25)

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2C) levels were higher than the corresponding preintervention values (p = 0.040 and p = 0.042, respectively)