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References Uchino, S., Bellomo, R., Goldsmith, D., Bates, S

& Djuranovic, S

In preparing this narrative review, we performed a comprehensive search of relevant peer-reviewed literature using databases such as PubMed, Scopus, and Google Scholar

They observed that clinical symptoms of withdrawal disappeared or improved markedly and rapidly in 97% of inpatients with alcohol dependence and 87% of those with opiate dependence.19 Apart from headaches in a few, all patients tolerated the treatment well

The tablet strengths 1.5 mg, 4 mg, 9 mg and 25 mg daily therefore look much larger on paper while delivering comparable clinical effect to much smaller injected doses