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We are excited about these findings because they offer the chance to now be able to share with patients: You have the characteristics that place you in a group of patients who respond remarkably to tirzepatide weight loss therapy. Or, by contrast, You have characteristics that suggest additional treatments might still be needed, said Scott Sands, PhD, associate professor of medicine at Brigham and Womens Hospital, Harvard Medical School, in a news release

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These structural deformations occur during native PrP (PrPc) misfolding to give the pathogenic PrPsc variant that produces amyloidogenesis (Snchez-Lpez et al., 2018)

Though both students face challenges, their underlying difficulties are quite different