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Mechanism of Action: Inhibits the destruction of acetylcholine by cholinesterase Indications: Myasthenia Gravis (MG) Myasthenia gravis (MG) is an autoimmune disorder caused by the development of autoantibodies that destroy acetylcholine receptors in the neuromuscular junction, resulting in muscle weakness (Gilhus, 2016)
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Although not a significant function of the PPP, it can operate to metabolize dietary pentose sugars derived from the digestion of nucleic acids as well as to rearrange the carbon skeletons of dietary carbohydrates into glycolytic and /or gluconeogenic intermediates
Andreeff M , Jiang S, Zhang X, Konopleva M, Estrov Z, Snell VE, Xie Z, Okcu MF, Sanchez-Williams G, Dong J, Estey EH, Champlin RC, Kornblau SM, Reed JC, Zhao S
Feb 27 2023;2(2):Cd015244
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