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Starting metformin extended-release and titrating GLP-1 therapy slowly (typically over 46 weeks) minimizes tolerability issues and improves adherence
The Cellular Continuum : The surge of cAMP is not uniform
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If taken with insulin or an insulin secretagogue (ie sulfonylurea) it is best to talk to your health care provider about possibly lowering the dose of these medications to lower the risk of hypoglycemia
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