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SURMOUNT-1 DXA substudy: tirzepatide in non-diabetic obesity, approximately 25% lean fraction
The data source for this study was the Optum Research Database, which contains de-identified enrollment, medical, and pharmacy claims data for commercial and Medicare Advantage patients
Additionally, in murine models exposed to dexamethasone, it was observed that the excretion of N-methylhistidinea marker indicative of muscle protein breakdownappeared reduced to a greater extent by IGF-1 LR3, potentially threefold more than by IGF-I
Tirzepatide and semaglutide are primarily used to help manage blood sugar levels in people with type 2 diabetes
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