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Clinical effects of L-Carnitine supplementation on physical performance in healthy subjects, the key to success in rehabilitation: A systematic review and Meta-Analysis from the rehabilitation point of view
When oxygen availability is limited, glucose is the most metabolically efficient fuel, and during myocardial ischemia, the ratio of acetyl-CoA/CoA in mitochondria increases, leading to the activation of pyruvate dehydrogenase (PDH) kinase, which in turn phosphorylates PDH to inhibit its activity
Under hyperglycemic conditions, mesangial cellderived exosomes have been shown to upregulate transforming growth factor-beta (TGF-) expression and activate the TGF-1/PI3KAkt signaling pathway, ultimately promoting podocyte injury and fibrotic remodeling (113)
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Sonia SB, Rahman MS, Shirin M, Siddiki MN, Sultana S, Chowdhury IH, Rumu H, Shamsuddoha N
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