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The prevalence of metabolic dysfunction in autoimmune disease may relate to chronic inflammation, corticosteroid therapy, reduced physical activity due to disease burden, or shared genetic susceptibilities
When this balance is disrupted, it may lead to bloating, irregular digestion, and increased sensitivity to foods
Mice treated with GLP-1 do not show a conditioned place preference to alcohol (Shirazi et al., 2013) and alcohol-preferring rats injected with EX4 reduce their operant responding for an alcohol solution (Davis et al., 2013)
Treatment typically begins at 2.5 mg weekly for four weeks, followed by increases of 2.5 mg every four weeks as tolerated
