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Here, the GIP fragments GIP(15-42), GIP(15-30), GIP(16-30) and GIP(17-30) were characterized as weak antagonists at the human GIP receptor in vitro , and the amino acids number 6-30 are required for effective GIP receptor antagonism as a high-affinity binding domain ( Figure 1 )

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HIV-1 myristoylated Nef treatment of murine microglial cells activates inducible nitric oxide synthase, NO 2 production and neurotoxic activity