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Some of our preliminary observations in 2026 suggest that the steady, continuous delivery of a patch may actually lessen the intensity of these side effects for some patients, as it avoids the sharp peak in medication concentration that occurs a day or two after an injection

Lancet 397(10278):971984 Shi I, Khan SS, Yeh RW, Ho JE, Dahabreh IJ, Kazi DS (2025) Semaglutide Eligibility Across All Current Indications for US Adults

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