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Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity
In summary, this study underscores the pivotal role of eryptosis in the anemia associated with LC, particularly in patients undergoing cytostatic treatment
Type 1 diabetes impairs the activity of rat testicular somatic and germ cells through NRF2/NLRP3 pathway-mediated oxidative stress
In vivo studies confirmed that Ghrelin significantly activated the BMP6/SMAD1 signaling pathway in the brain tissue of AD mice, thereby inhibiting microglial ferroptosis, promoting microglial polarization toward the M2 phenotype, and ameliorating learning and memory deficits in AD mice ( In vitro , Neuritin activated the phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway in A 1-42 -stimulated HT22 neuronal cells, leading to increased NADK activity and NADPH expression, reduced MDA and ROS levels, and inhibition of neuronal ferroptosis
(PubMed) Singh SV, Powolny AA, Stan SD, et al
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