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(1) The quaternary ammonium structure of ipratropium carries a positive charge, limiting its systemic absorption and preventing significant penetration into the central nervous system, thereby confining its effects primarily to the pulmonary system
The role of mitochondrial OXPHOS dysfunction in the development of neurologic diseases
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One hundred microliters of each cell resuspension for each condition was transferred to a 96-well microtiter plate (Corning, 3904), from which the fluorescence (GFPexcitation = 475 nm
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