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doi: 10.1016/j.dld.2021.02.011 24

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It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products

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Aberrant activation of signaling pathways and therapeutic implications Taken together, the aberrant activation of signaling pathways such as PI3K-AKT-mTOR, MAPK, NF-B, TGF-, Wnt/-catenin, JAK/STAT, Notch, Hippo-YAP/TAZ, and GAS6/AXL contributes extensively to therapy resistance across cancer types (Fig

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