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Abbreviations ASCVD: Atherosclerotic cardiovascular disease GLP-1: Glucagon-like peptide-1 SGLT2: Sodium-glucose cotransporter 2 References American Diabetes Association Professional Practice Committee (2024) 9

Graphical Abstract Similar content being viewed by others Introduction Glucagon-like peptide-1 (GLP-1) receptor agonists and sodium-glucose cotransporter 2 inhibitors (SGLT2) are key treatments for type 2 diabetes that improve cardiovascular and renal outcomes [1,2,3]

GLP-1R are also found in smooth muscle cells in the walls of arteries in kidneys and lungs, myocytes of the sinoatrial node of the heart, and Brunners glands of gastrointestinal tract (3)

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doi: 10.1093/JAC/20.6.815 14 BaltzerS