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Another arginine transporter, CAT-2 ( SLC7A2 ), is highly expressed in BRAF (v-raf murine sarcoma viral oncogene homolog B1) inhibitor-resistant melanoma, displaying metabolic reprogramming from glucose to arginine dependence (Li Y
In addition, we suggest that selenium deficiency enhances susceptibility to ferroptotic processes, as well as other programmed cell death pathways due to a reduction in GPx4 activity
It is involved in detoxification processes, the mobilisation of toxins, the discharge of heavy metals as well as the neutralisation of free radicals
2024 Apr 10;13(8):2176
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