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Studies in rats exposed to circadian-disrupting xenobiotics showed Epithalon prevented disturbances in diurnal dopamine rhythms in the median eminence and normalized norepinephrine dynamics in the medial preoptic area
REDEFINE 1 adults with overweight/obesity, no diabetes GI adverse events were reported in 79.6% of CagriSema participants vs 39.9% on placebo
Known GLP-1 side effects include: nausea, vomiting, diarrhea, dizziness, increased heart rate, infections, headaches, indigestion, pancreatitis, medullary thyroid cancer, sudden kidney injury, worsening diabetic-related retinopathy, shortness of breath, wheezing, hives, difficulty swallowing, rash, abdominal pain and feelings of doom or dread
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