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[20] Both subunits of the GST dimer, whether hetero- or homodimeric in nature, contain a single nonsubstrate binding site, as well as a GSH-binding site

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Sleep and recovery impact: Caffeines stimulating effect may delay sleep onset and lower sleep quality, reducing the nightly testosterone surge that occurs during deep rest

Its mechanism is purely metabolic: it directly targets lipid metabolism via inhibition of NNMT and restoration of cellular NAD+

And when independent researchers went hunting for the gene that would build it in the human genome, in our gut bacteria they couldn't find it