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It's attracted growing interest in research circles because of how directly it targets a specific enzymatic pathway - which makes it a useful tool for studying how NNMT activity influences downstream metabolic signalling at the cellular level

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The combined effect is sustainable and safe weight loss for people who take a GLP-1 agonist medication under medical supervision, according to a clinical review of GLP-1 receptor agonists published in Drugs in Context

Figure 2), which can cause oxidative damage to proteins, nucleic acids, amino acids, and lipids, in addition to increased mitochondrial and cellular damage and death

Blauwendraat, C., Nalls, M