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In the US, the Food and Drug Administration (FDA) has warned that some patients are turning to unapproved versions of GLP-1 drugs, including semaglutide and tirzepatide, for weight loss

On top of that, many factors increase the difficulty of losing and maintaining weight

These pipeline medications can treat rare genetic diseases which can cause obesity, help manage diabetes while helping with weight loss, and can also help with weight loss alone

The gap between those two figures is where most unpleasant surprises live

Studies, including research from the National Institute on Drug Abuse (NIDA), show that repeated opioid exposure leads to structural brain changes, increasing the risk of addiction